ZYTIGA 250mg - Abiraterone by Janssen

    ZYTIGA

    250mg
    Oncology Medications

    ZYTIGA250mg

    ZYTIGA (abiraterone acetate) 250mg tablets are the original formulation of this androgen synthesis inhibitor for metastatic prostate cancer, taken as four tablets on an empty stomach.

    Generic Name:Abiraterone
    Manufacturer:Janssen

    Key Benefits

    • Established efficacy in clinical trials
    • Original formulation with extensive experience
    • Oral administration
    • Authentic Janssen product

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    How ZYTIGA Works

    1

    ZYTIGA 250mg works identically to the 500mg formulation—by irreversibly inhibiting CYP17A1 to block androgen synthesis at all sites (testes, adrenals, and tumor). The difference is in formulation and administration requirements.

    2

    The 250mg tablet is formulated for fasting administration, requiring an empty stomach (no food for 2 hours before and 1 hour after dosing) for optimal absorption.

    About ZYTIGA 250mg

    ZYTIGA (abiraterone acetate) 250mg by Janssen is the original formulation that established a new treatment paradigm for metastatic castration-resistant prostate cancer. This strength requires taking four 250mg tablets (1000mg total) once daily on an empty stomach. ZYTIGA 250mg remains an option for patients who may have difficulty with the 500mg formulation or have specific clinical considerations. Both formulations provide equivalent therapeutic benefit when taken correctly. As an androgen biosynthesis inhibitor, ZYTIGA blocks CYP17A1 enzyme in the testes, adrenal glands, and tumor cells, providing more complete androgen suppression than castration alone. This translates to significant improvements in overall survival. Pharmacy Remedy supplies both ZYTIGA formulations to ensure patients and healthcare providers have access to the most appropriate option.

    Common Uses

    • Metastatic castration-resistant prostate cancer
    • Metastatic castration-sensitive prostate cancer

    Dosage Information

    Standard Dosing:

  1. 1000 mg (four 250mg tablets) orally once daily on EMPTY stomach
  2. No food for 2 hours before and 1 hour after dosing
  3. Take with prednisone 5 mg twice daily
  4. Continue ADT
  5. Swallowing Difficulty:

  6. Tablets may be dissolved in water but must still be taken on empty stomach
  7. Always consult with a qualified healthcare professional for proper dosing. This information is for reference only.

    Storage & Handling

    Store at 20°C to 25°C (68°F to 77°F). Excursions permitted between 15°C and 30°C (59°F and 86°F). No refrigeration required.

    We ensure proper cold chain handling during shipping to maintain product integrity.

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