VESANOID
10mgVESANOID10mg
VESANOID (Tretinoin/ATRA) 10mg capsules by Roche — differentiation therapy for acute promyelocytic leukemia (APL). ATRA+ATO: 97% CR, 90%+ cure rate.
Key Benefits
- 97% complete remission with ATRA+ATO protocol
- 90%+ long-term cure rate — most curable AML subtype
- Differentiation therapy — unique mechanism of action
- Oral capsules — convenient administration
- Room temperature storage — no cold chain needed
- Emergency supply available for urgent APL cases
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How VESANOID Works
Tretinoin (ATRA) induces terminal differentiation of leukemic promyelocytes by degrading the PML-RARα fusion oncoprotein caused by t(15;17) translocation. This releases the block on myeloid differentiation, forcing immature cancer cells to mature into functional granulocytes.
About VESANOID 10mg
VESANOID (Tretinoin/All-Trans Retinoic Acid) 10mg capsules by Roche is the revolutionary differentiation therapy that transformed acute promyelocytic leukemia (APL) from 75% fatal to 90%+ curable. Unlike conventional chemotherapy, ATRA forces leukemic promyelocytes to differentiate into mature granulocytes by degrading the PML-RARα fusion oncoprotein. The ATRA+ATO (arsenic trioxide) protocol achieves 97% complete remission and 99% overall survival at 50 months — making APL the most curable form of acute myeloid leukemia, without conventional chemotherapy. As a licensed pharmaceutical supplier, we maintain emergency stock of Vesanoid for urgent APL supply with express shipping worldwide.
Common Uses
- Acute promyelocytic leukemia (APL/AML-M3) — induction therapy
- APL with t(15;17) translocation / PML-RARα fusion
- ATRA+ATO protocol (low/intermediate-risk APL)
- ATRA+chemotherapy (high-risk APL)
Dosage Information
Adults: 45mg/m²/day orally in 2 divided doses. Children: 25mg/m²/day. Continue until CR or maximum 90 days. Take with food.
Always consult with a qualified healthcare professional for proper dosing. This information is for reference only.
Storage & Handling
Store at 15-25°C (59-77°F). Protect from light and heat. Keep in original packaging. No refrigeration required.
We ensure proper cold chain handling during shipping to maintain product integrity.
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