CEREZYME 400 U/10mL - Imiglucerase by Sanofi Genzyme

    CEREZYME

    400 U/10mL
    Specialty Medications

    CEREZYME400 U/10mL

    CEREZYME (Imiglucerase) 400 U/10mL is an enzyme replacement therapy by Sanofi Genzyme for the treatment of Type 1 and Type 3 Gaucher disease.

    Generic Name:Imiglucerase
    Manufacturer:Sanofi Genzyme

    Key Benefits

    • Over 30 years of proven clinical efficacy and safety
    • Reduces hepatosplenomegaly within 6-12 months
    • Normalizes blood counts (hemoglobin and platelets)
    • Prevents and stabilizes skeletal disease
    • Improves quality of life and energy levels
    • Well-established dosing guidelines across all ages

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    How CEREZYME Works

    1

    Cerezyme (Imiglucerase) is a recombinant form of the enzyme glucocerebrosidase. It catalyzes the hydrolysis of glucocerebroside to glucose and ceramide in the lysosomes of macrophages, thereby reducing the pathological accumulation that causes the symptoms of Gaucher disease.

    About CEREZYME 400 U/10mL

    CEREZYME (Imiglucerase) 400 U/10mL by Sanofi Genzyme is the world's first and most established enzyme replacement therapy (ERT) for Gaucher disease — a rare inherited lysosomal storage disorder affecting approximately 1 in 40,000-60,000 people worldwide. Gaucher disease is caused by a deficiency of the enzyme glucocerebrosidase (GCase), leading to accumulation of glucocerebroside in macrophages throughout the body. This results in hepatosplenomegaly (enlarged liver and spleen), bone disease including avascular necrosis and pathological fractures, anemia, thrombocytopenia, and impaired quality of life. Cerezyme replaces the deficient enzyme through biweekly intravenous infusions, effectively reversing or preventing the hematological, visceral, and skeletal manifestations of the disease. With over 30 years of clinical experience since its approval in 1994, Cerezyme has the most extensive long-term safety and efficacy data of any Gaucher disease treatment. As a licensed pharmaceutical supplier based in Turkey, we provide authentic Sanofi Genzyme CEREZYME with complete cold chain handling (2-8°C), certificate of authenticity, and competitive wholesale pricing for hospitals, specialty pharmacies, and rare disease treatment centers worldwide.

    Common Uses

    • Type 1 Gaucher disease (non-neuronopathic)
    • Type 3 Gaucher disease (chronic neuronopathic)
    • Pediatric and adult patients with Gaucher disease
    • Long-term enzyme replacement therapy

    Dosage Information

    Initial dose: 60 U/kg IV every 2 weeks. Maintenance: 15-60 U/kg every 2 weeks, individualized based on clinical response. Each vial contains 400 Units. Reconstitute with 10.2 mL sterile water, then dilute in 0.9% NaCl to 100-200 mL for infusion over 1-2 hours.

    Always consult with a qualified healthcare professional for proper dosing. This information is for reference only.

    Storage & Handling

    Store at 2-8°C (36-46°F). Do not freeze. Protect from light. After reconstitution, diluted solution is stable for up to 24 hours at 2-8°C. Ship with validated cold chain packaging and temperature monitoring.

    We ensure proper cold chain handling during shipping to maintain product integrity.

    Frequently Asked Questions About CEREZYME

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